A Multi-tasking Dentifrice for the 21st Century, Anti-hypersensitivity mechanism of action for a dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, 0.243% NaF and specially-designed silica

Lynette Zaidel / Yun Po Zhang, Ph.D., DDS (Hon)

Article date: Thursday, April 05, 2012 02:00 AM (EST)
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Article: A Multi-tasking Dentifrice for the 21st Century
Author: Serge Dibart, DMD & Yun Po Zhang, PhD, DDs (Hons)

In this fast paced, esthetic/health conscious society, the development of a multiple benefit dentifrice for everyday use that can successfully alleviate dentin hypersensitivity in addition to protecting teeth against dental caries, and removing plaque and stains, and reducing gingivitis is a needed addition to our preventive armamentarium.  This multi-tasking, cost efficient and easy to use product containing specially-designed silica should have its place, next to the toothbrush, in every household’s bathroom vanity.

Upon completion of reading this article, the clinician will be able to:

  • know that this multi-tasking dentifrice that contains 0.3% triclosan, 2% PVM/MA copolymer, 0.243% NaF and specially-designed silica provides benefits in reducing sensitivity, gingivitis, plaque, cavity, tartar, stains, and oral malodour.


Article: Anti-hypersensitivity mechanism of action for a dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, 0.243% NaF and specially-designed silica
Author: Lynette Zaidel, Phd, Rahul Patel, Bs, Sarita Mello, Phd, Rodman Heu, Ms, Michael Stranick Phd, Suman Chopra, PhD & Michael Prencipe, Phd

The dentin occlusion efficacy and effects on dentin permeability of a new multi-benefit dentifrice containing 0.3% triclosan, 2% PVM/MA copolymer, 0.243% NaF, and specially-designed silica was compared with three other dentifrices using microscopy, chemical analysis and hydraulic conductance.

Upon completion of reading this article, the clinician will be able to:

  • Understand the technology approaches used to treat dentin hypersensitivity and

  • Understand the measurement techniques used in the laboratory to probe the occlusion effects on dentin tubules and the important aspects to incorporate in the laboratory models to better predict clinical efficacy.

Target audience: Dentists, Hygienists and Assistants.

Release date: Thursday, April 05, 2012
Expiration date: Sunday, April 05, 2015

"A Multi-tasking Dentifrice for the 21st Century, Anti-hypersensitivity mechanism of action for a dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, 0.243% NaF and specially-designed silica" is co-sponsored by Dental Tribune America, LLC. Dental Tribune America LLC is a recognized ADA CERP provider.

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Lynette Zaidel

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Lynette Zaidel works as a Senior Technical Associate at Colgate-Palmolive Company in Piscataway, New Jersey, USA. She has 13 years of experience in oral care research and development, including development of whitening, sensitivity and erosion protection technologies and measurement methods development. Her work has been reported in 12 presentations at IADR/AADR conferences.

Lynette received her doctorate in chemistry from the University of Illinois, Urbana.

 

Yun Po Zhang , Ph.D., DDS (Hon)

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Dr. Yun-Po Zhang is Director of Clinical Dental Research at Colgate-Palmolive Company in Piscataway, New Jersey, USA. He has primary responsibility for the clinical program for emerging markets, in addition to playing several important roles to support oral care business around the world.

Dr. Zhang holds three US patents in dental caries prevention, and has over 130 publications in international dental and scientific journals.  He has been invited to speak at many international dental meetings and has served as a keynote speaker at some events.  He is currently serving on the editorial board for the Journal of Dental Research which is a top-ranked international journal on oral biology.  In addition, he also serves on the AADR scholarship committee.

Dr. Zhang has received numerous awards throughout his training and career.  Most recently, he has been awarded as an Honorary Member of the American Dental Association, received the honorary title of Senior Clinical Investigator (professor rank) from Forsyth/Harvard University, and obtained the “Outstanding 50 Asian Americans in Business Award” by the Asian American Business Development Center.   

Dr. Zhang graduated from the Northeastern University in Boston, Massachusetts, receiving a PhD degree in Physical Chemistry.  His post-doctoral training was at Forsyth/Harvard School of Dental Medicine in Oral Biology.  He has been awarded a certificate of MBA executive program from the Wharton Business School of the University of Pennsylvania.  He has also been awarded an Honorary Degree in Dentistry by the Dalian Medical University in China.

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