Colgate Oral Health Network
Offenbacher Symposium Podcast Series – Part 3: Precision Oral Health
Kimon Divaris Panos N. Papapanou Silvana P. Barros
Kimon Divaris DDS, PhD, Panos N. Papapanou DDS, PhD, Silvana P. Barros DDS, PhD

Medicine and dentistry are moving toward personalized, or precision, approaches to care, which involve properly classifying people to effectively customize prevention, diagnosis, and treatment. Achieving precision health requires making sense of big data at both the population and molecular levels. This podcast explains the concept of biologically informed stratification of periodontal disease and the role it can play in accelerating the development of precision oral medicine.

After completing this podcast, listeners should be able to:

  • Gain an understanding of the concept of biologically informed stratification of periodontal disease and its implications for preventing, predicting, and managing periodontitis.
Kimon Divaris

Kimon Divaris DDS, PhD

Data that describe the periodontal microbiome in elderly individuals are lacking. This presentation reviews the primary findings from an ancillary study of oral health in dentate individuals older than 65 years, with a focus on subgingival bacterial patterns and their relation to the severity and extent of periodontitis.

After completing this podcast, listeners should be able to:

  • Identify key observations from the WHICAP Ancillary Study of Oral Health, as they relate to subgingival bacterial profiles and clinical periodontal status in a cohort of elderly individuals (>65 years old).
Panos N. Papapanou

Panos N. Papapanou DDS, PhD

Globally, periodontitis is one of the most prevalent chronic inflammatory diseases. Both the inflammation and microbial dysbiosis that occur in periodontal disease can lead to compromised barrier function of the gingival epithelia. This podcast reviews how the pathogen P. gingivalis disrupts barrier function of epithelial cells by inducing epigenetic alterations and identifies potential treatments, for further investigation, to inhibit these events.

After completing this podcast, listeners should be able to:

  • Understand how infection with P. gingivalis induces epigenetic changes that alter gene expression, and how this knowledge has led to potential new strategies to treat periodontal disease.
Silvana P. Barros

Silvana P. Barros DDS, PhD

Kimon Divaris

Kimon Divaris DDS, PhD

More courses with Kimon Divaris

Kimon Divaris, DDS, PhD is a Professor of Pediatric Dentistry in the Division of Pediatric and Public Health at the Adams School of Dentistry, in the University of North Carolina at Chapel Hill. A board-certified pediatric dentist, he is actively involved in clinical practice, research, and teaching at all levels. He is an oral and genetic epidemiologist. His NIH-funded research program lies at the intersection of clinical, biological, and public health research for precision oral health applications with emphasis on dental caries and periodontal disease. He is the recipient of several major awards and has had substantial scholarly and editorial activity.

Financial disclosure: Kimon Divaris has received an honorarium from Colgate-Palmolive Company.
Panos N. Papapanou

Panos N. Papapanou DDS, PhD

More courses with Panos N. Papapanou

Panos N. Papapanou, DDS, PhD is Professor of Dental Medicine, Director of the Division of Periodontics, and Chairman of the Section of Oral, Diagnostic and Rehabilitation Sciences at the College of Dental Medicine at Columbia University. He has earned DDS degrees from the University of Athens and Columbia University, a PhD from Göteborg University in Sweden, and has received post-doctoral training in Oral Microbiology at the Forsyth Institute in Cambridge, MA. His research has been funded by the National Institutes of Health, foundations and industry, and encompasses studies of the epidemiology of periodontal disease, the assessment of microbial and host-derived risk factors, the pathobiology of periodontitis, and its role as a general health stressor. He is the recipient of several international awards, including the Jens Waerhaug Prize from the Scandinavian Society of Periodontology (1988), the William Gies Award for Clinical Research from the International Association for Dental Research (2015), the Yngve Ericsson Prize in Prophylactic Dentistry Research jointly awarded by Swedish Patent Revenue Fund for Prophylactic Odontology and the European Organization for Caries Research (2016), the Distinguished Scientist Award for Basic Research in Periodontal Disease from the International Association for Dental Research (2017), and the International Research Prize from the Swedish Dental Association (2021). He is a Fellow of the American College of Dentists, Past President and Past Councilor of the Periodontal Research Group of the IADR, and the Editor-in-Chief of the Journal of Clinical Periodontology. He has published over 190 original manuscripts and currently has a Google Scholar h-index of 77 with >24,500 bibliographic citations.

Financial disclosure: Panos N. Papapanou has received an honorarium from Colgate-Palmolive Company.
Silvana P. Barros

Silvana P. Barros DDS, PhD

More courses with Silvana P. Barros

Silvana Barros, DDS, MS. PhD is Director of Clinical Innovation at Colgate Palmolive. She previously served as Professor of the Department of Comprehensive Oral Health Periodontology at the University of North Carolina at Chapel Hill with activities involving clinical practice, teaching, mentorship of grad students and postdocs on translational and clinical research. Dr. Barros received from the American Academy of Periodontology (AAP) the awards for Outstanding Teaching and Mentoring in Periodontics and Clinical Research Award, she also was a recipient of the UNC Creativity Hub Inaugural Award focusing on Transdisciplinary Approaches for Precision Research. She is the Past President of the NC division of the American Association for Dental Research (ADR) and a member of the advisory board of several scientific journals Dr. Barros is internationally recognized for her work on the generation of the genomics evidence base and epigenetics as a modifiable risk factor in periodontal diseases and on the association of periodontal disease and systemic health.

Financial disclosure: Silvana P. Barros has received an honorarium from Colgate-Palmolive Company.
Language: EnglishC.E. credits: 0.75Start date: March 18, 2022Expiration date: March 18, 2025AGD PACE subject code(s): 490